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Thioredoxin and Thioredoxin Reductase Control Tissue Factor Activity by Thiol Redox-dependent Mechanism

Abnormally enhanced tissue factor (TF) activity is related to increased thrombosis risk in which oxidative stress plays a critical role. Human cytosolic thioredoxin (hTrx1) and thioredoxin reductase (TrxR), also secreted into circulation, have the power to protect against oxidative stress. However,...

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Detalhes bibliográficos
Main Authors: Wang, Pei, Wu, Yunfei, Li, Xiaoming, Ma, Xiaofeng, Zhong, Liangwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561554/
https://ncbi.nlm.nih.gov/pubmed/23223577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418046
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