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The role of the priming loop in Influenza A virus RNA synthesis
RNA-dependent RNA polymerases (RdRps) are used by RNA viruses to replicate and transcribe their RNA genomes1. They adopt a closed, right-handed fold with conserved subdomains called palm, fingers, and thumb1,2. Conserved RdRp motifs A-F coordinate the viral RNA template, NTPs, and magnesium ions to...
Enregistré dans:
| Publié dans: | Nat Microbiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888940/ https://ncbi.nlm.nih.gov/pubmed/27274864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.29 |
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