HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP

Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the mechanisms that mediate their transport to mitochondria are poorly characterized. Using affinity RNA pull-down followed by mass spectrometry analysis, we found two RNA-binding proteins (RBPs), HuR (human antigen R)...

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Podrobná bibliografie
Vydáno v:Genes Dev
Hlavní autoři: Noh, Ji Heon, Kim, Kyoung Mi, Abdelmohsen, Kotb, Yoon, Je-Hyun, Panda, Amaresh C., Munk, Rachel, Kim, Jiyoung, Curtis, Jessica, Moad, Christopher A., Wohler, Christina M., Indig, Fred E., de Paula, Wilson, Dudekula, Dawood B., De, Supriyo, Piao, Yulan, Yang, Xiaoling, Martindale, Jennifer L., de Cabo, Rafael, Gorospe, Myriam
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888842/
https://ncbi.nlm.nih.gov/pubmed/27198227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276022.115
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