HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP

Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the mechanisms that mediate their transport to mitochondria are poorly characterized. Using affinity RNA pull-down followed by mass spectrometry analysis, we found two RNA-binding proteins (RBPs), HuR (human antigen R)...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Noh, Ji Heon, Kim, Kyoung Mi, Abdelmohsen, Kotb, Yoon, Je-Hyun, Panda, Amaresh C., Munk, Rachel, Kim, Jiyoung, Curtis, Jessica, Moad, Christopher A., Wohler, Christina M., Indig, Fred E., de Paula, Wilson, Dudekula, Dawood B., De, Supriyo, Piao, Yulan, Yang, Xiaoling, Martindale, Jennifer L., de Cabo, Rafael, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888842/
https://ncbi.nlm.nih.gov/pubmed/27198227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276022.115
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