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Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins

The bioavailability of members of the transforming growth factor β (TGF-β) family is controlled by a number of mechanisms. Bona fide TGF-β is sequestered into the matrix in a latent state and must be activated before it can bind to its receptors. Here, we review the molecules and mechanisms that reg...

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Publicat a:Cold Spring Harb Perspect Biol
Autors principals: Robertson, Ian B., Rifkin, Daniel B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888822/
https://ncbi.nlm.nih.gov/pubmed/27252363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a021907
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