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Voltage-Gated Na(+) Channels: Not Just for Conduction

Voltage-gated sodium channels (VGSCs), composed of a pore-forming α subunit and up to two associated β subunits, are critical for the initiation of the action potential (AP) in excitable tissues. Building on the monumental discovery and description of sodium current in 1952, intrepid researchers des...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Biol
Main Authors: Kruger, Larisa C., Isom, Lori L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888818/
https://ncbi.nlm.nih.gov/pubmed/27252364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a029264
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