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Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals

BACKGROUND: Ankyrin repeats and LEM domain containing protein 1 (Ankle1) belongs to the LEM protein family, whose members share a chromatin-interacting LEM motif. Unlike most other LEM proteins, Ankle1 is not an integral protein of the inner nuclear membrane but shuttles between the nucleus and the...

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Pubblicato in:BMC Cell Biol
Autori principali: Zlopasa, Livija, Brachner, Andreas, Foisner, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888674/
https://ncbi.nlm.nih.gov/pubmed/27245214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0102-z
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