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Molecular clock of HIV-1 envelope genes under early immune selection

BACKGROUND: The molecular clock hypothesis that genes or proteins evolve at a constant rate is a key tool to reveal phylogenetic relationships among species. Using the molecular clock, we can trace an infection back to transmission using HIV-1 sequences from a single time point. Whether or not a str...

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Publicado en:Retrovirology
Main Authors: Park, Sung Yong, Love, Tanzy M. T., Perelson, Alan S., Mack, Wendy J., Lee, Ha Youn
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888660/
https://ncbi.nlm.nih.gov/pubmed/27246201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0269-6
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