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Molecular clock rates at loci under stabilizing selection.

Under stabilizing selection in a finite population, lambda, the rate of allelic substitutions at a locus is approximately lambda approximately mu(1 + S)-1/2, where mu is the mutation rate. S, the stringency of selection upon new mutants, is defined by S = NVm/Vs, where N is the population size and V...

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Bibliographic Details
Main Author: Foley, P
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC299463/
https://ncbi.nlm.nih.gov/pubmed/3479776
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