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Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells
Amiloride-sensitive epithelial Na(+) channels (ENaC) regulate fluid balance in the alveoli and are regulated by oxidative stress. Since glutathione (GSH) is the predominant antioxidant in the lungs, we proposed that changes in glutathione redox potential (E(h)) would alter cell signaling and have an...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Am J Physiol Lung Cell Mol Physiol |
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Prif Awduron: | , , , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
American Physiological Society
2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888545/ https://ncbi.nlm.nih.gov/pubmed/25713321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00213.2014 |
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