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Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells

Amiloride-sensitive epithelial Na(+) channels (ENaC) regulate fluid balance in the alveoli and are regulated by oxidative stress. Since glutathione (GSH) is the predominant antioxidant in the lungs, we proposed that changes in glutathione redox potential (E(h)) would alter cell signaling and have an...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Lung Cell Mol Physiol
Egile Nagusiak: Downs, Charles A., Kreiner, Lisa, Zhao, Xing-Ming, Trac, Phi, Johnson, Nicholle M., Hansen, Jason M., Brown, Lou Ann, Helms, My N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888545/
https://ncbi.nlm.nih.gov/pubmed/25713321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00213.2014
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