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Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells
Amiloride-sensitive epithelial Na(+) channels (ENaC) regulate fluid balance in the alveoli and are regulated by oxidative stress. Since glutathione (GSH) is the predominant antioxidant in the lungs, we proposed that changes in glutathione redox potential (E(h)) would alter cell signaling and have an...
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| izdano v: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888545/ https://ncbi.nlm.nih.gov/pubmed/25713321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00213.2014 |
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