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Implications of using whole genome sequencing to test unselected populations for high risk breast cancer genes: a modelling study

BACKGROUND: The decision to test for high risk breast cancer gene mutations is traditionally based on risk scores derived from age, family and personal cancer history. Next generation sequencing technologies such as whole genome sequencing (WGS) make wider population testing more feasible. In the UK...

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Detalhes bibliográficos
Publicado no:Hered Cancer Clin Pract
Main Authors: Warren-Gash, Charlotte, Kroese, Mark, Burton, Hilary, Pharoah, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888520/
https://ncbi.nlm.nih.gov/pubmed/27252788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-016-0052-7
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