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Implications of using whole genome sequencing to test unselected populations for high risk breast cancer genes: a modelling study

BACKGROUND: The decision to test for high risk breast cancer gene mutations is traditionally based on risk scores derived from age, family and personal cancer history. Next generation sequencing technologies such as whole genome sequencing (WGS) make wider population testing more feasible. In the UK...

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I publikationen:Hered Cancer Clin Pract
Huvudupphovsmän: Warren-Gash, Charlotte, Kroese, Mark, Burton, Hilary, Pharoah, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888520/
https://ncbi.nlm.nih.gov/pubmed/27252788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-016-0052-7
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