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SCF/c-kit transactivates CXCR4-serine 339 phosphorylation through G protein-coupled receptor kinase 6 and regulates cardiac stem cell migration

C-kit positive cardiac stem cells (CSCs) have been shown to contribute to myocardial regeneration after infarction. Previously, we have shown that the c-kit ligand stem cell factor (SCF) can induce CSC migration into the infarcted area during myocardial infarction (MI). However, the precise mechanis...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zuo, Ke, Kuang, Dong, Wang, Ying, Xia, Yanli, Tong, Weilin, Wang, Xiaoyan, Chen, Yaobin, Duan, Yaqi, Wang, Guoping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887787/
https://ncbi.nlm.nih.gov/pubmed/27245949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26812
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