miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT

BACKGROUND: Gain-of-function mutations and overexpression of KIT are characteristic features of gastrointestinal stromal tumor (GIST). Dysregulation in miRNA expression may lead to KIT overexpression and tumorigenesis. METHODS: miRNA microarray analysis and real-time PCR were used to determine the m...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Wang, Yu, Li, Jun, Kuang, Dong, Wang, Xiaoyan, Zhu, Yuanli, Xu, Sanpeng, Chen, Yaobing, Cheng, Henghui, Zhao, Qiu, Duan, Yaqi, Wang, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902930/
https://ncbi.nlm.nih.gov/pubmed/29661252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0228-z
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