ROCK2 mediates the proliferation of pulmonary arterial endothelial cells induced by hypoxia in the development of pulmonary arterial hypertension

It has been reported that RhoA activation and Rho-kinase (ROCK) expression are increased in chronic hypoxic lungs, and the long-term inhibition of ROCK markedly improves the survival of patients with pulmonary arterial hypertension (PAH). However, whether Rho-kinase α (ROCK2) participates in regulat...

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Vydáno v:Exp Ther Med
Hlavní autoři: QIAO, FENG, ZOU, ZHITIAN, LIU, CHUNHUI, ZHU, XIAOFENG, WANG, XIAOQIANG, YANG, CHENGPENG, JIANG, TENGJIAO, CHEN, YING
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887771/
https://ncbi.nlm.nih.gov/pubmed/27284349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3214
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