IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence()()

Head and neck squamous cell carcinomas (HNSCC) exhibit a small population of uniquely tumorigenic cancer stem cells (CSC) endowed with self-renewal and multipotency. We have recently shown that IL-6 enhances the survival and tumorigenic potential of head and neck cancer stem cells (i.e. ALDH(high)CD...

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Détails bibliographiques
Publié dans:Neoplasia
Auteurs principaux: Finkel, Kelsey A., Warner, Kristy A., Kerk, Samuel, Bradford, Carol R., McLean, Scott A., Prince, Mark E., Zhong, Haihong, Hurt, Elaine M., Hollingsworth, Robert E., Wicha, Max S., Tice, David A., Nör, Jacques E.
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press 2016
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Original article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887598/
https://ncbi.nlm.nih.gov/pubmed/27237319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.03.004
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