IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence()()

Head and neck squamous cell carcinomas (HNSCC) exhibit a small population of uniquely tumorigenic cancer stem cells (CSC) endowed with self-renewal and multipotency. We have recently shown that IL-6 enhances the survival and tumorigenic potential of head and neck cancer stem cells (i.e. ALDH(high)CD...

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Vydáno v:Neoplasia
Hlavní autoři: Finkel, Kelsey A., Warner, Kristy A., Kerk, Samuel, Bradford, Carol R., McLean, Scott A., Prince, Mark E., Zhong, Haihong, Hurt, Elaine M., Hollingsworth, Robert E., Wicha, Max S., Tice, David A., Nör, Jacques E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2016
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887598/
https://ncbi.nlm.nih.gov/pubmed/27237319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.03.004
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