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Mechanisms of ferroptosis

Ferroptosis is a non-apoptotic form of cell death that can be triggered by small molecules or conditions that inhibit glutathione biosynthesis or the glutathione-dependent antioxidant enzyme glutathione peroxidase 4 (GPX4). This lethal process is defined by the iron-dependent accumulation of lipid r...

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Bibliografiske detaljer
Udgivet i:Cell Mol Life Sci
Main Authors: Cao, Jennifer Yinuo, Dixon, Scott J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887533/
https://ncbi.nlm.nih.gov/pubmed/27048822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2194-1
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