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Mechanisms of ferroptosis
Ferroptosis is a non-apoptotic form of cell death that can be triggered by small molecules or conditions that inhibit glutathione biosynthesis or the glutathione-dependent antioxidant enzyme glutathione peroxidase 4 (GPX4). This lethal process is defined by the iron-dependent accumulation of lipid r...
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Publicado no: | Cell Mol Life Sci |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer International Publishing
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887533/ https://ncbi.nlm.nih.gov/pubmed/27048822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2194-1 |
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