Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration

Hyperhomocysteinemia (HHcy) accelerates atherosclerosis by increasing proliferation and stimulating cytokine secretion in T cells. However, whether homocysteine (Hcy)-mediated T cell activation is associated with metabolic reprogramming is unclear. Here, our in vivo and in vitro studies showed that...

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Detaylı Bibliyografya
Yayımlandı:Protein Cell
Asıl Yazarlar: Feng, Juan, Lü, Silin, Ding, Yanhong, Zheng, Ming, Wang, Xian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Higher Education Press 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887324/
https://ncbi.nlm.nih.gov/pubmed/26856873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0245-x
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