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Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication
Replisome assembly requires the loading of replicative hexameric helicases onto origins by AAA+ ATPases. How loader activity is appropriately controlled remains unclear. Here, we use structural and biochemical analyses to establish how an antimicrobial phage protein interferes with the function of t...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887207/ https://ncbi.nlm.nih.gov/pubmed/27244442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14158 |
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