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Spatial signals link exit from mitosis to spindle position

In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14. There are two competing models that explain MEN regul...

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Vydáno v:eLife
Hlavní autoři: Falk, Jill Elaine, Tsuchiya, Dai, Verdaasdonk, Jolien, Lacefield, Soni, Bloom, Kerry, Amon, Angelika
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887205/
https://ncbi.nlm.nih.gov/pubmed/27166637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14036
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