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Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis
Skin homeostasis is maintained by the continuous proliferation and differentiation of epidermal cells. The skin forms a strong but flexible barrier against microorganisms as well as physical and chemical insults; however, the physiological mechanisms that maintain this barrier are not fully understo...
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| Publicat a: | J Clin Invest |
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| Autors principals: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887165/ https://ncbi.nlm.nih.gov/pubmed/27111231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82887 |
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