Public T cell receptors confer high-avidity CD4 responses to HIV controllers

The rare patients who are able to spontaneously control HIV replication in the absence of therapy show signs of a particularly efficient cellular immune response. To identify the molecular determinants that underlie this response, we characterized the T cell receptor (TCR) repertoire directed at Gag...

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Publicado en:J Clin Invest
Autores principales: Benati, Daniela, Galperin, Moran, Lambotte, Olivier, Gras, Stéphanie, Lim, Annick, Mukhopadhyay, Madhura, Nouël, Alexandre, Campbell, Kristy-Anne, Lemercier, Brigitte, Claireaux, Mathieu, Hendou, Samia, Lechat, Pierre, de Truchis, Pierre, Boufassa, Faroudy, Rossjohn, Jamie, Delfraissy, Jean-François, Arenzana-Seisdedos, Fernando, Chakrabarti, Lisa A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887161/
https://ncbi.nlm.nih.gov/pubmed/27111229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83792
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