HIV Controller CD4+ T Cells Respond to Minimal Amounts of Gag Antigen Due to High TCR Avidity

HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral treatment. Emerging evidence indicates that HIV control is mediated through very active cellular immune responses, though how such responses can persist over time without immune exhaustion...

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Detalhes bibliográficos
Main Authors: Vingert, Benoît, Perez-Patrigeon, Santiago, Jeannin, Patricia, Lambotte, Olivier, Boufassa, Faroudy, Lemaître, Fabrice, Kwok, William W., Theodorou, Ioannis, Delfraissy, Jean-François, Thèze, Jacques, Chakrabarti, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829066/
https://ncbi.nlm.nih.gov/pubmed/20195518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000780
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