HIV Controller CD4+ T Cells Respond to Minimal Amounts of Gag Antigen Due to High TCR Avidity

HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral treatment. Emerging evidence indicates that HIV control is mediated through very active cellular immune responses, though how such responses can persist over time without immune exhaustion...

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Autori principali: Vingert, Benoît, Perez-Patrigeon, Santiago, Jeannin, Patricia, Lambotte, Olivier, Boufassa, Faroudy, Lemaître, Fabrice, Kwok, William W., Theodorou, Ioannis, Delfraissy, Jean-François, Thèze, Jacques, Chakrabarti, Lisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829066/
https://ncbi.nlm.nih.gov/pubmed/20195518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000780
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