In situ structural analysis of the human nuclear pore complex

Nuclear pore complexes (NPCs) are fundamental components of all eukaryotic cells that mediate nucleocytoplasmic exchange. Elucidating their 110 MDa structure imposes a formidable challenge and requires in situ structural biology approaches. Fifteen out of about thirty nucleoporins (Nups) are structu...

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Pubblicato in:Nature
Autori principali: von Appen, Alexander, Kosinski, Jan, Sparks, Lenore, Ori, Alessandro, DiGuilio, Amanda L., Vollmer, Benjamin, Mackmull, Marie-Therese, Banterle, Niccolo, Parca, Luca, Kastritis, Panagiotis, Buczak, Katarzyna, Mosalaganti, Shyamal, Hagen, Wim, Andres-Pons, Amparo, Lemke, Edward A., Bork, Peer, Antonin, Wolfram, Glavy, Joseph S., Bui, Khanh Huy, Beck, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886846/
https://ncbi.nlm.nih.gov/pubmed/26416747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15381
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