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In situ structural analysis of the human nuclear pore complex
Nuclear pore complexes (NPCs) are fundamental components of all eukaryotic cells that mediate nucleocytoplasmic exchange. Elucidating their 110 MDa structure imposes a formidable challenge and requires in situ structural biology approaches. Fifteen out of about thirty nucleoporins (Nups) are structu...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886846/ https://ncbi.nlm.nih.gov/pubmed/26416747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15381 |
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