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Histone H3 globular domain acetylation identifies a new class of enhancers

Histone acetylation is generally associated with active chromatin, but most studies have focused on the acetylation of histone tails. Various histone H3 and H4 tail acetylations mark the promoters of active genes1. This includes acetylation of H3 on lysine 27 (H3K27ac), which blocks the deposition o...

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Détails bibliographiques
Publié dans:Nat Genet
Auteurs principaux: Pradeepa, Madapura M, Grimes, Graeme R, Kumar, Yatendra, Olley, Gabrielle, Taylor, Gillian C A, Schneider, Robert, Bickmore, Wendy A
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886833/
https://ncbi.nlm.nih.gov/pubmed/27089178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3550
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