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The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC

While the role of high-risk human papillomavirus (HPV) oncoproteins E6 and E7 in targeting p53 and retinoblastoma (Rb) has been intensively studied, how E6 and E7 manipulate cellular signaling cascades to promote the viral life cycle and cancer development is less understood. Keratinocytes containin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Strickland, Sydney Webb, Vande Pol, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886775/
https://ncbi.nlm.nih.gov/pubmed/27030265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00411-16
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