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Platelet-derived SDF1 primes pulmonary capillary vascular niche to drive lung alveolar regeneration
The lung alveoli regenerate after surgical removal of the left lobe by pneumonectomy (PNX). How this alveolar regrowth/regeneration is initiated remains unknown. We found that activated platelets trigger lung regeneration by supplying stromal cell-derived-factor1 (SDF1/CXCL12). After PNX, platelets...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886751/ https://ncbi.nlm.nih.gov/pubmed/25621952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3096 |
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