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Critical Points in Tumorigenesis: A Carcinogen Initiated Phase Transition Analyzed via Single Cell Proteomics

A kinetic, single cell proteomic study of chemically-induced carcinogenesis is interpreted by treating the single cell data as fluctuations of an open system transitioning between different steady states. In analogy to a first-order transition, phase coexistence and the loss of degrees of freedom ar...

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Publicado en:Small
Main Authors: Poovathingal, Suresh Kumar, Kravchenko-Balasha, Nataly, Shin, Young Shik, Levine, R. D., Heath, James R.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886749/
https://ncbi.nlm.nih.gov/pubmed/26780498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201501178
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