Pcdh19 Loss-of-Function Increases Neuronal Migration In Vitro but is Dispensable for Brain Development in Mice

Protocadherin 19 (Pcdh19) is an X-linked gene belonging to the protocadherin superfamily, whose members are predominantly expressed in the central nervous system and have been implicated in cell-cell adhesion, axon guidance and dendrite self-avoidance. Heterozygous loss-of-function mutations in huma...

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Publicado no:Sci Rep
Main Authors: Pederick, Daniel T., Homan, Claire C., Jaehne, Emily J., Piltz, Sandra G., Haines, Bryan P., Baune, Bernhard T., Jolly, Lachlan A., Hughes, James N., Gecz, Jozef, Thomas, Paul Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886214/
https://ncbi.nlm.nih.gov/pubmed/27240640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26765
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