Role of phosphodiesterase 4 expression in the Epac1 signaling‐dependent skeletal muscle hypertrophic action of clenbuterol

Clenbuterol (CB), a selective β (2)‐adrenergic receptor (AR) agonist, induces muscle hypertrophy and counteracts muscle atrophy. However, it is paradoxically less effective in slow‐twitch muscle than in fast‐twitch muscle, though slow‐twitch muscle has a greater density of β‐AR. We recently demonstr...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Ohnuki, Yoshiki, Umeki, Daisuke, Mototani, Yasumasa, Shiozawa, Kouichi, Nariyama, Megumi, Ito, Aiko, Kawamura, Naoya, Yagisawa, Yuka, Jin, Huiling, Cai, Wenqian, Suita, Kenji, Saeki, Yasutake, Fujita, Takayuki, Ishikawa, Yoshihiro, Okumura, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886163/
https://ncbi.nlm.nih.gov/pubmed/27207782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12791
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