The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency.

Homozygosity for the severe combined immunodeficiency (scid) mutation results in a block in T- and B-lymphocyte development. An unusually high incidence of spontaneous thymic lymphoma development was observed after transfer of this mutation from the C.B-17 congenic strain background onto the diabete...

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Bibliographic Details
Main Authors: Prochazka, M, Gaskins, H R, Shultz, L D, Leiter, E H
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC48852/
https://ncbi.nlm.nih.gov/pubmed/1373493
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