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TSGΔ154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation

Tumor susceptibility gene 101 (TSG101) elicits an array of cellular functions, including promoting cytokinesis, cell cycle progression and proliferation, as well as facilitating endosomal trafficking and viral budding. TSG101 protein is highly and aberrantly expressed in various human cancers. Speci...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chua, Huey-Huey, Huang, Chiun-Sheng, Weng, Pei-Lun, Yeh, Te-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884989/
https://ncbi.nlm.nih.gov/pubmed/26811492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6973
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