Patient-derived xenograft (PDX) tumors increase growth rate with time

Patient-derived xenograft (PDX) models are frequently used for translational cancer research, and are assumed to behave consistently as the tumor ages. However, growth rate constancy as a function of time is unclear. Notably, variable PDX growth rates over time might have implications for the interp...

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Udgivet i:Oncotarget
Main Authors: Pearson, Alexander T., Finkel, Kelsey A., Warner, Kristy A., Nör, Felipe, Tice, David, Martins, Manoela D., Jackson, Trachette L., Nör, Jacques E.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884970/
https://ncbi.nlm.nih.gov/pubmed/26783960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6919
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