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Bispecific antibodies and CARs: generalized immunotherapeutics harnessing T cell redirection
To realize the full potential of cancer immunotherapy, the latest generation immunotherapeutics are designed to harness the potent tumor-killing capacity of T cells. Thus, to mobilize T cells, new optimized bispecific antibody (BsAb) designs, enabling efficient polyclonal redirection of cytotoxic ac...
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| Pubblicato in: | Curr Opin Immunol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884546/ https://ncbi.nlm.nih.gov/pubmed/26963133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.02.006 |
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