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Bispecific antibodies and CARs: generalized immunotherapeutics harnessing T cell redirection

To realize the full potential of cancer immunotherapy, the latest generation immunotherapeutics are designed to harness the potent tumor-killing capacity of T cells. Thus, to mobilize T cells, new optimized bispecific antibody (BsAb) designs, enabling efficient polyclonal redirection of cytotoxic ac...

詳細記述

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書誌詳細
出版年:Curr Opin Immunol
主要な著者: Zhukovsky, Eugene A., Morse, Richard J., Maus, Marcela V.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884546/
https://ncbi.nlm.nih.gov/pubmed/26963133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.02.006
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