Activation of GPR30 improves exercise capacity and skeletal muscle strength in senescent female Fischer344×Brown Norway rats

The molecular mechanisms of muscle weakness and sarcopenia in postmenopausal women are largely unknown. To determine the effect of a new estrogen receptor, GPR30, in the maintenance of exercise capacity and skeletal muscle function in females, the selective GPR30 agonist, G1 (100 μg/kg/day), or vehi...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Wang, Hao, Alencar, Allan, Lin, Marina, Sun, Xuming, Sudo, Roberto T., Zapata-Sudo, Gisele, Lowe, Dawn A., Groban, Leanne
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884542/
https://ncbi.nlm.nih.gov/pubmed/27173878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.05.040
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