Directional Phosphorylation and Nuclear Transport of the Splicing Factor SRSF1 Is Regulated by an RNA Recognition Motif()

Multisite phosphorylation is required for the biological function of serine-arginine (SR) proteins, a family of essential regulators of mRNA splicing. These modifications are catalyzed by serine-arginine protein kinases (SRPKs) that phosphorylate numerous serines in arginine-serine-rich (RS) domains...

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Publicado en:J Mol Biol
Main Authors: Serrano, Pedro, Aubol, Brandon E., Keshwani, Malik M., Forli, Stefano, Ma, Chen-Ting, Dutta, Samit K., Geralt, Michael, Wüthrich, Kurt, Adams, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884534/
https://ncbi.nlm.nih.gov/pubmed/27091468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.04.009
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