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Directional Phosphorylation and Nuclear Transport of the Splicing Factor SRSF1 Is Regulated by an RNA Recognition Motif()

Multisite phosphorylation is required for the biological function of serine-arginine (SR) proteins, a family of essential regulators of mRNA splicing. These modifications are catalyzed by serine-arginine protein kinases (SRPKs) that phosphorylate numerous serines in arginine-serine-rich (RS) domains...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Biol
Prif Awduron: Serrano, Pedro, Aubol, Brandon E., Keshwani, Malik M., Forli, Stefano, Ma, Chen-Ting, Dutta, Samit K., Geralt, Michael, Wüthrich, Kurt, Adams, Joseph A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884534/
https://ncbi.nlm.nih.gov/pubmed/27091468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.04.009
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