Emergence of undifferentiated colonies from mouse embryonic stem cells undergoing differentiation by retinoic acid treatment

Retinoic acid (RA) is one of the most potent inducers of differentiation of mouse embryonic stem cells (ESCs). However, previous studies show that RA treatment of cells cultured in the presence of a leukemia inhibitory factor (LIF) also result in the upregulation of a gene called Zscan4, whose trans...

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Veröffentlicht in:In Vitro Cell Dev Biol Anim
Hauptverfasser: Sharova, Lioudmila V., Sharov, Alexei A., Piao, Yulan, Stagg, Carole A., Amano, Tomokazu, Qian, Yong, Dudekula, Dawood, Schlessinger, David, Ko, Minoru S.H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884469/
https://ncbi.nlm.nih.gov/pubmed/27130680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-016-0013-5
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