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Emergence of undifferentiated colonies from mouse embryonic stem cells undergoing differentiation by retinoic acid treatment

Retinoic acid (RA) is one of the most potent inducers of differentiation of mouse embryonic stem cells (ESCs). However, previous studies show that RA treatment of cells cultured in the presence of a leukemia inhibitory factor (LIF) also result in the upregulation of a gene called Zscan4, whose trans...

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Bibliografiske detaljer
Udgivet i:In Vitro Cell Dev Biol Anim
Main Authors: Sharova, Lioudmila V., Sharov, Alexei A., Piao, Yulan, Stagg, Carole A., Amano, Tomokazu, Qian, Yong, Dudekula, Dawood, Schlessinger, David, Ko, Minoru S.H.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884469/
https://ncbi.nlm.nih.gov/pubmed/27130680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-016-0013-5
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