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Synthetic long read sequencing reveals the composition and intraspecies diversity of the human microbiome

Identifying bacterial strains in metagenome and microbiome samples using computational analyses of short-read sequence remains a difficult problem. Here, we present an analysis of a human gut microbiome using on Tru-seq synthetic long reads combined with new computational tools for metagenomic long-...

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Vydáno v:Nat Biotechnol
Hlavní autoři: Kuleshov, Volodymyr, Jiang, Chao, Zhou, Wenyu, Jahanbani, Fereshteh, Batzoglou, Serafim, Snyder, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884093/
https://ncbi.nlm.nih.gov/pubmed/26655498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3416
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