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Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein

Mammalian BET proteins comprise a family of bromodomain-containing epigenetic regulators with complex functions in chromatin organization and gene regulation. We identified the sole member of the BET protein family in Drosophila, Fs(1)h, as an inhibitor of the stress responsive transcription factor...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chatterjee, Nirmalya, Tian, Min, Spirohn, Kerstin, Boutros, Michael, Bohmann, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883770/
https://ncbi.nlm.nih.gov/pubmed/27233051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006072
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