Inhibition of Nuclear Transport of NF-ĸB p65 by the Salmonella Type III Secretion System Effector SpvD

Salmonella enterica replicates in macrophages through the action of effector proteins translocated across the vacuolar membrane by a type III secretion system (T3SS). Here we show that the SPI-2 T3SS effector SpvD suppresses proinflammatory immune responses. SpvD prevented activation of an NF-ĸB-dep...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Rolhion, Nathalie, Furniss, R. Christopher D., Grabe, Grzegorz, Ryan, Aindrias, Liu, Mei, Matthews, Sophie A., Holden, David W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883751/
https://ncbi.nlm.nih.gov/pubmed/27232334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005653
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