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Somatic Expression of Herpes Thymidine Kinase in Mice following Injection of a Fusion Gene into Eggs

A plasmid, designated pMK, containing the structural gene for thymidine kinase from herpes simplex virus (HSV) fused to the promoter/regulatory region of the mouse metallothionein-I gene, was injected into the pronucleus of fertilized one-cell mouse eggs; the eggs were subsequently reimplanted into...

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Publicado en:Cell
Autores principales: Brinster, Ralph L., Chen, Howard Y., Trumbauer, Myrna, Senear, Allen W., Warren, Raphael, Palmiter, Richard D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1981
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883678/
https://ncbi.nlm.nih.gov/pubmed/6276022
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