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Active Tissue Stiffness Modulation Controls Valve Interstitial Cell Phenotype and Osteogenic Potential in 3D Culture
Calcific aortic valve disease (CAVD) progression is a highly dynamic process whereby normally fibroblastic valve interstitial cells (VIC) undergo osteogenic differentiation, maladaptive extracellular matrix (ECM) composition, structural remodeling, and tissue matrix stiffening. However, how VIC with...
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| Pubblicato in: | Acta Biomater |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4883663/ https://ncbi.nlm.nih.gov/pubmed/26947381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.03.007 |
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