Active Tissue Stiffness Modulation Controls Valve Interstitial Cell Phenotype and Osteogenic Potential in 3D Culture

Calcific aortic valve disease (CAVD) progression is a highly dynamic process whereby normally fibroblastic valve interstitial cells (VIC) undergo osteogenic differentiation, maladaptive extracellular matrix (ECM) composition, structural remodeling, and tissue matrix stiffening. However, how VIC with...

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Detaylı Bibliyografya
Yayımlandı:Acta Biomater
Asıl Yazarlar: Duan, Bin, Yin, Ziying, Hockaday, Laura A., Magin, Richard L., Butcher, Jonathan T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883663/
https://ncbi.nlm.nih.gov/pubmed/26947381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.03.007
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