Degradation of Akt Using Protein Catalyzed Capture Agents

Abnormal signaling of the protein kinase Akt has been shown to contribute to human diseases such as diabetes and cancer, but Akt has proven to be a challenging target for drugging. Using iterative in situ click chemistry we recently developed multiple protein catalyzed capture (PCC) agents that allo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Pept Sci
Main Authors: Henning, Ryan K., Varghese, Joseph O., Das, Samir, Nag, Arundhati, Tang, Grace, Tang, Kevin, Sutherland, Alexander M., Heath, James R.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883657/
https://ncbi.nlm.nih.gov/pubmed/26880702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.2858
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker