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Access of protective antiviral antibody to neuronal tissues requires CD4 T cell help

Circulating antibodies can access most tissues to mediate surveillance and elimination of invading pathogens. Immunopriviledged tissues such as the brain and the peripheral nervous system, are shielded from plasma proteins, by the blood-brain barrier(1) and blood nerve barrier(2), respectively. Yet,...

詳細記述

保存先:
書誌詳細
出版年:Nature
主要な著者: Iijima, Norifumi, Iwasaki, Akiko
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883597/
https://ncbi.nlm.nih.gov/pubmed/27225131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17979
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